For Immediate Release April 22, 2021

Montreal, Quebec, Canada – (GLOBE NEWSWIRE) – Sunshine Biopharma Inc. (OTC PINK:  “SBFM”), a pharmaceutical company focused on the research, development and  commercialization of oncology and antiviral drugs, today announced that RB Capital has injected an additional investment of $500,000 to augment the Company’s Coronavirus drug  development program. In addition, RB Capital has provided the Company with assurances that  it will continue to provide funding over the next 30 days for the Company’s other R&D activities,  including Ada-27a anticancer drug. 

Sunshine Biopharma’s CFO, Camille Sebaaly stated, “We are very pleased to continue our  relationship with RB Capital as long-term investor in the Company. They truly understand our  vision and are prepared to help us reach our exciting drug development objectives.” 

Deborah Braun of RB Capital Partners Inc. stated, “Given their recent success with initial mice  studies for their COVID-19 treatment, the tremendous progress with Adva-27a research and development, and the new e-commerce platform, we are happy to double our investment in  Sunshine Biopharma. We understand that financial resources are required to reach the various  milestones leadership has put into place for the Company and are pleased to support this  growth and progress. With this added investment the Company has the resources necessary to  bring these drugs to market faster than previously anticipated.” 

About Sunshine Biopharma’s Coronavirus (COVID-19) Treatment 

Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) is the causative agent of the ongoing COVID-19 pandemic that has claimed the lives of over 3 million people worldwide since  it first appeared in December 2019. There are currently no drugs that can effectively arrest  replication of the virus in people who have contracted the illness. On May 22, 2020, Sunshine  Biopharma filed a provisional patent application for several molecules which were designed by  computer-aided modeling to inhibit the Coronavirus proteases, thus shutting down the ability of  the virus to multiply. Sunshine Biopharma has since completed the synthesis of four such  molecules and identified a lead compound, SBFM-PL4. On February 1, 2021, Sunshine 

Biopharma entered into an exclusive license agreement with the University of Georgia for two  Anti-Coronavirus compounds which the University of Georgia had previously developed and  patented. The Company is currently advancing the development of these two compounds in  parallel with its own SBFM-PL4 by conducting a transgenic mice study in collaboration with the  University of Georgia, College of Pharmacy. The mice being used in the study have been 

genetically engineered to express the human angiotensin-converting enzyme 2 (hACE2)  transmembrane protein in their lungs making them susceptible to lethal infection by SARS-CoV 2. The SARS-CoV-2 virus uses the hACE2 receptor to gain entry into human cells to replicate.  The goal of the study is to determine if these protease inhibitors will protect the hACE2- transgenic mice from disease progression and death following infection with SARS-CoV-2.  Should these mice studies prove successful, Sunshine Biopharma plans to submit the results to  the FDA for authorization to conduct testing on actual COVID-19 patient volunteers in a Phase I  clinical trial setting. 

About Adva-27a Anticancer Drug 

In addition, to working on the development of a treatment for COVID-19, Sunshine Biopharma is  engaged in the development Adva-27a, a unique anticancer compound. Tests conducted to  date have demonstrated the effectiveness of Adva-27a at destroying Multidrug Resistant  Cancer Cells, including Pancreatic Cancer cells, Small-Cell Lung Cancer cells, Breast Cancer  cells, and Uterine Sarcoma cells. Clinical trials for Pancreatic Cancer indication are planned to  be conducted at McGill University’s Jewish General Hospital in Montreal, Canada. Sunshine  Biopharma is owner of all patents and intellectual property pertaining to Adva-27a. 

Safe Harbor Forward-Looking Statements 

This press release may contain forward looking statements which are based on current expectations, forecasts, and  assumptions that involve risks as well as uncertainties that could cause actual outcomes and results to differ  materially from those anticipated or expected, including statements related to the amount and timing of expected  revenues statements related to our financial performance, expected income, distributions, and future growth for  upcoming quarterly and annual periods. These risks and uncertainties are further defined in filings and reports by  the Company with the U.S. Securities and Exchange Commission (SEC). Actual results and the timing of certain  events could differ materially from those projected in or contemplated by the forward-looking statements due to a  number of factors detailed from time to time in our filings with the SEC. Among other matters, the Company may not  be able to sustain growth or achieve profitability based upon many factors including but not limited to general stock  market conditions. Reference is hereby made to cautionary statements set forth in the Company’s most recent SEC  filings. We have incurred and will continue to incur significant expenses in our expansion of our existing as well as  new service lines noting there is no assurance that we will generate enough revenues to offset those costs in both the  near and long term. Additional service offerings may expose us to additional legal and regulatory costs and  unknown exposure(s) based upon the various geopolitical locations we will be providing services in, the impact of  which cannot be predicted at this time. 

For Additional Information Contact: 

Camille Sebaaly, CFO 

Sunshine Biopharma Inc. 

Direct Line: 514-814-0464 

[email protected]